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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.68694687 |
| Normalized Enrichment Score (NES) | -1.5836254 |
| Nominal p-value | 0.0036563072 |
| FDR q-value | 0.11325035 |
| FWER p-Value | 0.857 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | STAT5A | 2680458 | 905 | 2.165 | -0.0100 | No | ||
| 2 | GRB2 | 6650398 | 957 | 2.091 | 0.0246 | No | ||
| 3 | HRAS | 1980551 | 1652 | 1.391 | 0.0121 | No | ||
| 4 | BAD | 2120148 | 2276 | 0.964 | -0.0042 | No | ||
| 5 | JAK2 | 3780528 6100692 6550577 | 3956 | 0.262 | -0.0899 | No | ||
| 6 | EPOR | 5290435 | 4224 | 0.215 | -0.1005 | No | ||
| 7 | RPS6KB1 | 1450427 5080110 6200563 | 4328 | 0.202 | -0.1024 | No | ||
| 8 | MAP2K2 | 4590601 | 4513 | 0.178 | -0.1091 | No | ||
| 9 | SOS1 | 7050338 | 4633 | 0.165 | -0.1126 | No | ||
| 10 | SNAI2 | 2100519 | 5530 | 0.100 | -0.1590 | No | ||
| 11 | LYN | 6040600 | 5783 | 0.087 | -0.1711 | No | ||
| 12 | GRAP2 | 7100441 1410647 | 6376 | 0.065 | -0.2018 | No | ||
| 13 | PIK3R1 | 4730671 | 7165 | 0.043 | -0.2434 | No | ||
| 14 | DOK1 | 1050279 2680112 5220273 | 7603 | 0.035 | -0.2664 | No | ||
| 15 | AKT1 | 5290746 | 7808 | 0.031 | -0.2768 | No | ||
| 16 | EPO | 940180 | 7886 | 0.030 | -0.2804 | No | ||
| 17 | MAP2K1 | 840739 | 8442 | 0.019 | -0.3099 | No | ||
| 18 | PTPN11 | 2230100 2470180 6100528 | 9168 | 0.008 | -0.3489 | No | ||
| 19 | PTPRO | 1940576 6370332 | 9491 | 0.003 | -0.3661 | No | ||
| 20 | PIK3CA | 6220129 | 9883 | -0.003 | -0.3871 | No | ||
| 21 | SH2B3 | 4810451 4850128 | 11502 | -0.028 | -0.4738 | No | ||
| 22 | MITF | 380056 | 11505 | -0.028 | -0.4734 | No | ||
| 23 | GRB10 | 6980082 | 12415 | -0.048 | -0.5215 | No | ||
| 24 | KITLG | 2120047 6220300 | 13497 | -0.088 | -0.5781 | No | ||
| 25 | SPRED2 | 510138 540195 | 13713 | -0.100 | -0.5879 | No | ||
| 26 | SHC1 | 2900731 3170504 6520537 | 14198 | -0.138 | -0.6115 | No | ||
| 27 | SPRED1 | 6940706 | 14911 | -0.237 | -0.6456 | No | ||
| 28 | FOXO3 | 2510484 4480451 | 15027 | -0.263 | -0.6471 | No | ||
| 29 | CREBBP | 5690035 7040050 | 15330 | -0.349 | -0.6571 | No | ||
| 30 | MAPK3 | 580161 4780035 | 15356 | -0.356 | -0.6521 | No | ||
| 31 | MATK | 380687 1410603 | 15816 | -0.549 | -0.6670 | No | ||
| 32 | MAPK8 | 2640195 | 16187 | -0.761 | -0.6733 | Yes | ||
| 33 | KIT | 7040095 | 16331 | -0.857 | -0.6657 | Yes | ||
| 34 | MAP4K1 | 4060692 | 16352 | -0.869 | -0.6513 | Yes | ||
| 35 | PTPN6 | 4230128 | 16387 | -0.891 | -0.6372 | Yes | ||
| 36 | PTEN | 3390064 | 16854 | -1.207 | -0.6407 | Yes | ||
| 37 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16927 | -1.270 | -0.6218 | Yes | ||
| 38 | RAF1 | 1770600 | 17237 | -1.646 | -0.6090 | Yes | ||
| 39 | GSK3B | 5360348 | 17703 | -2.429 | -0.5907 | Yes | ||
| 40 | STAT1 | 6510204 6590553 | 17835 | -2.706 | -0.5493 | Yes | ||
| 41 | VAV1 | 6020487 | 17923 | -2.904 | -0.5021 | Yes | ||
| 42 | GAB1 | 2970156 | 17961 | -2.990 | -0.4506 | Yes | ||
| 43 | CBL | 6380068 | 18061 | -3.305 | -0.3968 | Yes | ||
| 44 | STAT3 | 460040 3710341 | 18169 | -3.701 | -0.3364 | Yes | ||
| 45 | CRKL | 4050427 | 18209 | -3.866 | -0.2694 | Yes | ||
| 46 | SOCS1 | 730139 | 18267 | -4.197 | -0.1974 | Yes | ||
| 47 | PDPK1 | 6650168 | 18323 | -4.496 | -0.1200 | Yes | ||
| 48 | TEC | 1400576 | 18571 | -7.590 | 0.0024 | Yes |
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